ISG15 counteracts Listeria monocytogenes infection
ISG15 is an interferon-stimulated, linear Coffee Airpots di-ubiquitin-like protein, with anti-viral activity.The role of ISG15 during bacterial infection remains elusive.We show that ISG15 expression in nonphagocytic cells is dramatically induced upon Listeria infection.Surprisingly this induction can be type I interferon independent and depends on